L-Lysine hydrochloride

CAS No. 657-27-2

L-Lysine hydrochloride( Lysine hydrochloride )

Catalog No. M21400 CAS No. 657-27-2

L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes increasing calcium absorption reducing diabetes-related illnesses and improving gut health.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Lysine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes increasing calcium absorption reducing diabetes-related illnesses and improving gut health.
  • Description
    L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes increasing calcium absorption reducing diabetes-related illnesses and improving gut health.(In Vivo):L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhances antioxidant activity. Pre- or post-treatment with L-lysine leads to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement is observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione. L-lysine supplementation almost completely ameliorates vascular calcification. Dietary L-lysine strongly suppresses plasma intact parathyroid hormone in adenine rats and supports a proper bone-vascular axis. The conserved orientation of the femoral apatite in group Lys also evidences the bone-protective effects of L-lysine. Dietary L-lysine elevates plasma alanine, proline, arginine, and homoarginine but not lysine. The dose-dependent delay in gastric emptying observed in rats is confirmed in humans with an increase in halftime of gastric emptying of 4 min/g L-lysine. Moreover, a dose-dependent increase in intestinal fluid accumulation is observed (0.4 mL/min/g L-lysine).
  • In Vitro
    ——
  • In Vivo
    L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhances antioxidant activity. Pre- or post-treatment with L-lysine leads to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement is observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione. L-lysine supplementation almost completely ameliorates vascular calcification. Dietary L-lysine strongly suppresses plasma intact parathyroid hormone in adenine rats and supports a proper bone-vascular axis. The conserved orientation of the femoral apatite in group Lys also evidences the bone-protective effects of L-lysine. Dietary L-lysine elevates plasma alanine, proline, arginine, and homoarginine but not lysine. The dose-dependent delay in gastric emptying observed in rats is confirmed in humans with an increase in halftime of gastric emptying of 4 min/g L-lysine. Moreover, a dose-dependent increase in intestinal fluid accumulation is observed (0.4 mL/min/g L-lysine).
  • Synonyms
    Lysine hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Inflammation/Immunology
  • Indication
    Pharyngitis

Chemical Information

  • CAS Number
    657-27-2
  • Formula Weight
    182.65
  • Molecular Formula
    C6H15ClN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:100 mg/mL (547.50 mM)
  • SMILES
    NCCCC[C@@H](C(O)=O)N.Cl
  • Chemical Name
    L-Lysine hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Al-Malki AL et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193.
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